Balance sheet of the liquidity contract with Natixis Oddo BHF SCA as of December 31, 2025

Strasbourg, January 12, 2026 – 06:00 p.m. CET

Under the liquidity contract entrusted by Transgene to Natixis Oddo BHF SCA, as of December 31, 2025, the following resources were managed through the liquidity account:

• 304,479 shares
• € 147,574.00

In the second half of 2025, a total of:

Purchases	348,958 shares	€ 389,221.00	988 market transactions
Sales	372,229 shares	€ 424,419.00	1,278 market transactions

It is recalled that when the liquidity program was initially established in 2016, the following resources were made available:

• € 500,000.00

At the time the liquidity program was transferred to Natixis Oddo BHF SCA on January 2, 2020, the resources managed through the liquidity account consisted of:

• 164,183 shares
• € 246,158.00

Contacts

Transgene: Lucie LARGUIER CFO +33 (0)3 88 27 91 00 investorrelations@transgene.fr

Attachment

• 20260112_BilanSemestriel_H2_2025_EN